APP-pT743 Polyclonal Antibody AE00295

520,00825,00

Phospho-specific rabbit polyclonal antibody to APP, phosphorylated T743 (APP-pT743)

See all our Alzheimer Protein antibodies

Official Symbol: APP

GeneID: 351

Swiss-Prot: P05067

Description

APP-pT743

All names and symbols: amyloid beta precursor protein; Amyloid-beta A4 protein; Alzheimer disease amyloid protein; Amyloid precursor protein; Cerebral vascular amyloid peptide; Protease nexin-II; alpha-sAPP; AAA; AD1; AD1I; PN2; ABPP; APP; APPI; CVAP; ABETA; PN2; PN-II; preA4; CTFgamma

Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Confirmed species reactivityHuman
Confirmed applicationsWB
Aeonian Rating®70
RRIDAB_2892785

Western Blot (WB):

AE00295 to APP-pT743 was successfully used to stain an approx. 120kDa band in lysates of mouse and rat brain lysates. Recommended concentration: 1-3ug/ml

WB of mouse and rat brain stained with APP-pT743 Rabbit Polyclonal Antibody AE00295
Mouse and rat brain with AE00295

Western Blot of a brain lysates (10ug) from mouse (lanes 1 and 2) and rat (lanes 3 and 4) stained with APP-pT743 Rabbit Polyclonal Antibody AE00295 at 1-2ug/ml (1h at ambient temp) in the presence (+) or absence (-) of its antigen (P peptide) or its non-phosphorylated control (C peptide). ECL staining by HRP.

ExpirationIntegrity warranted for 24 months after purchase when handled and stored according to instructions, see below.
Storage instructionsAvoid repeated freeze/thaw cycles. For long term storage, keep small aliquots at -20°C or -80°C and keep one aliquot at 4°C for daily experimentations. Azide will preserve antibody at 4°C for 6-12 months, when kept away from direct sun light.
WarrantyThis product is only warranted for the specifications as described in this product sheet and only when the product is handled and stored according to instructions. User should validate this antibody in the application and tissue/cell type as required, after confirmation of integrity upon receipt is obtained by reproducing the performance as described below. Should such confirmation not be attempted, any warranty is void. In case of non-conformance, user needs to contact us immediately for replacement or refund.
LiabilityThis product is for in vitro research use only. Any other applications, such as diagnostics or therapeutics, or in vivo experiments, and the validation of this product therein, are solely at the responsibility of the buyer/user.
Product Data Sheet
Material Safety Data Sheet

Additional information

Purification

Antigen-affinity purified from serum by sequential phospho-peptide and non-phospho-peptide affinity columns

Immunogen

A synthetic peptide around phosphorylated T743 of human APP (NP_000475.1)

Epitope

A short sequence around phosphorylated T743 (exact sequence is proprietary)

Cellular localization

all membranes

Positive Controls

brain

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

SKU: AE00295 Categories: , , , , , Tag: