Androgen Receptor Recombinant Antibody AE00344

$520,00$1.500,00

Specific, and tissue microarray-validated rabbit recombinant antibody clone AE367R to human Androgen Receptor

Official Symbol: AR

GeneID: 367

Swiss-Prot: P10275

For BSA-free at 1mg IgG/ml, please ask us for a quotation.

Description

Androgen Receptor

All names and symbols: Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AIS; AR; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM

Host speciesRabbit
ClonalityRecombinant
IsotypeIgG
Confirmed species reactivityHuman
Confirmed applicationsIHC
Aeonian Rating®95
RRIDAB_2916348

Immunohistochemistry (IHC):

AE00344 to Androgen Receptor was successfully used to stain nuclei in Sertoli and Leydig cells of human testis sections, and in epithelial and stromal cells of human prostate and seminal vesicle sections. Recommended concentration: 1-3ug/ml

IHC of human testis stained with Androgen Receptor Rabbit Recombinant Antibody AE00344
Human testis with AE00344

Formaldehyde-fixed, paraffin-embedded human testis stained with Androgen Receptor Rabbit Recombinant Antibody AE00344 at 1-2ug/ml for 60 minutes at 37°C. Epitope retrieval: Autoclave at 121°C, pH7.8 for 5 min followed by 20 min cooling. DAB staining by HRP polymer.

IHC of human prostate stained with Androgen Receptor Rabbit Recombinant Antibody AE00344
Human prostate with AE00344

Formaldehyde-fixed, paraffin-embedded human prostate stained with Androgen Receptor Rabbit Recombinant Antibody AE00344 at 1-2ug/ml for 60 minutes at 37°C. Epitope retrieval: Autoclave at 121°C, pH7.8 for 5 min followed by 20 min cooling. DAB staining by HRP polymer.

IHC of human seminal vesicle stained with Androgen Receptor Rabbit Recombinant Antibody AE00344
Human seminal vesicle with AE00344

Formaldehyde-fixed, paraffin-embedded human seminal vesicle stained with Androgen Receptor Rabbit Recombinant Antibody AE00344 at 1-2ug/ml for 60 minutes at 37°C. Epitope retrieval: Autoclave at 121°C, pH7.8 for 5 min followed by 20 min cooling. DAB staining by HRP polymer.

Tissue Microarray Validation:

Normal tissues

Strong positiveWeak to moderateNo staining at all
endometrium, proliferativebreastadipose
epididymisbronchial mucosaadrenal gland
fallopian tubeendometrium, secretoryaorta, media
prostateesophagus, squamous epitheliumappendix mucosa
seminal vesiclegallbladder epitheliumappendix muscular wall
skinileum mucosabone marrow
testislivercerebellum
lymph nodecerebrum
myometriumcolon muscular wall
ovarian stromaduodenum Brunner gland
pancreasduodenum mucosa
parotid glandheart muscle
placenta, earlylung
renal cortexparathyroid
skeletal musclepituitary gland
spleenplacenta mature
stomachrectum mucosa
thymusrenal medulla
thyroid gland
tonsil
urinary bladder muscular wall
urothelium
uterus

Cancer tissues

Strong positiveWeak to moderateNo staining at all
breast cancer no specific typeendometrioid carcinomaadrenocortical adenoma
hepatocellular carcinomahigh-grade serous carcinomacholangiocellular carcinoma
papillary renal cell carcinomaprostate small cell carcinomaclear cell renal cell carcinoma
prostate adenocarcinomasurothelial carcinomacolorectal adenocarcinoma
epitheloid malignant mesothelioma
esophagus adenocarcinoma
esophagus squamous cell carcinoma
gastric adenocarcinoma
gastrointestinal stromal tumor
leiomyosarcoma in soft tissue
lung adenocarcinoma
ovarian clear cell carcinoma
pancreas ductal adenocarcinoma
pancreas neuroendocrine tumor
pharynx squamous cell carcinoma
renal oncocytoma
seminoma
thyroid medullary carcinoma
thyroid, papillary cancer
ExpirationIntegrity warranted for 24 months after purchase when handled and stored according to instructions, see below.
Storage instructionsAvoid repeated freeze/thaw cycles. For long term storage, keep small aliquots at -20°C or -80°C and keep one aliquot at 4°C for daily experimentations. Azide will preserve antibody at 4°C for 6-12 months, when kept away from direct sun light.
WarrantyThis product is only warranted for the specifications as described in this product sheet and only when the product is handled and stored according to instructions. User should validate this antibody in the application and tissue/cell type as required, after confirmation of integrity upon receipt is obtained by reproducing the performance as described below. Should such confirmation not be attempted, any warranty is void. In case of non-conformance, user needs to contact us immediately for replacement or refund.
LiabilityThis product is for in vitro research use only. Any other applications, such as diagnostics or therapeutics, or in vivo experiments, and the validation of this product therein, are solely at the responsibility of the buyer/user.
Product Data Sheet
Material Safety Data Sheet

Additional information

Purification

By Protein A from bioreactor concentrate

Immunogen

Synthetic peptide corresponding to within aa1-100 region of Androgen Receptor

Epitope

Within aa 1-100 region

Cellular localization

nucleus

Positive Controls

cerebellum, endometrium, epididymis, ovary, prostate, seminal vesicle, skin, testis

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