Description
Mammaglobin-A
All names and symbols: Mammaglobin-A; secretoglobin family 2A member 2; mammaglobin A; mammaglobin-1; MGB1; UGB2; SCGB2A2
| Host species | Rabbit |
| Clonality | Recombinant |
| Isotype | IgG |
| Confirmed species reactivity | Human |
| Confirmed applications | IHC |
| Aeonian Rating® | 90 |
| RRID | AB_2921273 |
Immunohistochemistry (IHC):
AE00372 to Mammaglobin-A was successfully used to stain luminal cells in human breast, and endocervix, and tumour cells in invasive lobular carcinoma sections. Recommended concentration: 1-3 μg/ml
Formaldehyde-fixed, paraffin-embedded human breast stained with Mammaglobin-A Rabbit Recombinant Antibody AE00372 at 1-2 μg/ml for 60 minutes at 37°C. Epitope retrieval: Autoclave at 121°C, pH7.8 for 5 min followed by 20 min cooling. DAB staining by HRP polymer.
Formaldehyde-fixed, paraffin-embedded human endocervix stained with Mammaglobin-A Rabbit Recombinant Antibody AE00372 at 1-2 μg/ml for 60 minutes at 37°C. Epitope retrieval: Autoclave at 121°C, pH7.8 for 5 min followed by 20 min cooling. DAB staining by HRP polymer.
Formaldehyde-fixed, paraffin-embedded human invasive lobular carcinoma stained with Mammaglobin-A Rabbit Recombinant Antibody AE00372 at 1-2 μg/ml for 60 minutes at 37°C. Epitope retrieval: Autoclave at 121°C, pH7.8 for 5 min followed by 20 min cooling. DAB staining by HRP polymer.
Tissue Microarray Validation:
Normal tissues
| Strong positive | Weak to moderate | No staining at all |
|---|---|---|
| breast | endometrium pregnancy | adipose |
| endocervix | epididymis | aorta media |
| appendix mucosa | ||
| appendix muscular wall | ||
| bone marrow | ||
| bronchus mucosa | ||
| cerebellum | ||
| cerebrum | ||
| colon mucosa | ||
| colon muscular wall | ||
| duodenum Brunner gland | ||
| duodenum mucosa | ||
| ectocervix | ||
| esophagus squamous epithelium | ||
| fallopian tube | ||
| gallbladder | ||
| heart muscle | ||
| ileum mucosa | ||
| kidney | ||
| liver | ||
| lung | ||
| lymph node | ||
| myometrium | ||
| ovarian stroma | ||
| pancreas | ||
| parathyroid gland | ||
| parotid gland | ||
| pituitary gland posterior lobe | ||
| placenta | ||
| prostate | ||
| rectum mucosa | ||
| seminal vesicle | ||
| sinus paranasalis | ||
| skeletal muscle | ||
| skin | ||
| spleen | ||
| stomach | ||
| testis | ||
| thymus | ||
| thyroid gland | ||
| tonsil | ||
| urinary bladder muscular wall |
Cancer tissues
Low presence of positive erythrocyte signals are ignored
| Strong positive | Weak to moderate | No staining at all |
|---|---|---|
| endometrioid endometrial carcinoma | cholangiocarcinoma | |
| endometrioid ovarian carcinoma | clear cell renal cell carcinoma | |
| invasive lobular carcinoma | high-grade serous carcinoma | |
| pleomorphic adenoma | medullary thyroid cancer | |
| pancreas neuroendocrine tumor | ||
| pancreatic ductal adenocarcinoma | ||
| prostate adenocarcinoma | ||
| seminoma | ||
| small cell lung carcinoma | ||
| urothelial carcinoma |
| Expiration | Integrity warranted for 24 months after purchase when handled and stored according to instructions, see below. |
| Storage instructions | Avoid repeated freeze/thaw cycles. For long term storage, keep small aliquots at -20°C or -80°C and keep one aliquot at 4°C for daily experimentations. Azide will preserve antibody at 4°C for 6-12 months, when kept away from direct sun light. |
| Warranty | This product is only warranted for the specifications as described in this product sheet and only when the product is handled and stored according to instructions. User should validate this antibody in the application and tissue/cell type as required, after confirmation of integrity upon receipt is obtained by reproducing the performance as described below. Should such confirmation not be attempted, any warranty is void. In case of non-conformance, user needs to contact us immediately for replacement or refund. |
| Liability | This product is for in vitro research use only. Any other applications, such as diagnostics or therapeutics, or in vivo experiments, and the validation of this product therein, are solely at the responsibility of the buyer/user. |
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