Mucin 6 Recombinant Antibody AE00378

$520,00$1.500,00

Specific, and tissue microarray-validated rabbit recombinant antibody clone AE806R to human Mucin 6

Official Symbol: MUC6

GeneID: 4588

Swiss-Prot: Q6W4X9

For BSA-free at 1mg IgG/ml, please ask us for a quotation.

Description

Mucin 6

All names and symbols: Gastric mucin-6; Mucin 6, oligomeric mucus/gel-forming; Mucin-6; Muc6; Muc-6; Muc 6

Host speciesRabbit
ClonalityRecombinant
IsotypeIgG
Confirmed species reactivityHuman
Confirmed applicationsIHC
Aeonian Rating®90
RRIDAB_2924703

Immunohistochemistry (IHC):

AE00378 to Mucin 6 was successfully used to stain epithelium of seminal vesicle, gland cells at the base of stomach antrum, and tumor cells in colorectal adenocarcinoma sections. Recommended concentration: 1-3 μg/ml

IHC of human seminal vesicle stained with Mucin 6 Rabbit Recombinant Antibody AE00378
Human seminal vesicle with AE00378

Formaldehyde-fixed, paraffin-embedded human seminal vesicle stained with Mucin 6 Rabbit Recombinant Antibody AE00378 at 1-2 μg/ml for 60 minutes at 37°C. Epitope retrieval: Autoclave at 121°C, pH7.8 for 5 min followed by 20 min cooling. DAB staining by HRP polymer.

IHC of human stomach stained with Mucin 6 Rabbit Recombinant Antibody AE00378
Human stomach with AE00378

Formaldehyde-fixed, paraffin-embedded human stomach stained with Mucin 6 Rabbit Recombinant Antibody AE00378 at 1-2 μg/ml for 60 minutes at 37°C. Epitope retrieval: Autoclave at 121°C, pH7.8 for 5 min followed by 20 min cooling. DAB staining by HRP polymer.

IHC of human colorectal carcinoma stained with Mucin 6 Rabbit Recombinant Antibody AE00378
Human colorectal carcinoma with AE00378

Formaldehyde-fixed, paraffin-embedded human colorectal adenocarcinoma stained with Mucin 6 Rabbit Recombinant Antibody AE00378 at 1-2 μg/ml for 60 minutes at 37°C. Epitope retrieval: Autoclave at 121°C, pH7.8 for 5 min followed by 20 min cooling. DAB staining by HRP polymer.

Tissue Microarray Validation:

Normal tissues

Strong positiveWeak to moderateNo staining at all
duodenum Brunner glandendocervixadipose
epididymisadrenal gland
gallbladderaorta media
pancreas ductsappendix mucosa
seminal vesicleappendix muscular wall
stomachbone marrow
breast
cerebellum
cerebrum
colon mucosa
colon muscular wall
duodenum Brunner gland
duodenum mucosa
ectocervix
endometrium, proliferation
endometrium, secretion
esophagus squamous epithelium
fallopian tube
heart muscle
ileum mucosa
kidney
liver
lung
lymph node
myometrium
ovarian stroma
parathyroid gland
parotid gland
pituitary gland
placenta
prostate
rectum mucosa
skeletal muscle
skin
spleen
testis
thymus
thyroid gland
tonsil
urinary bladder muscular wall
urothelium

Cancer tissues

Strong positiveWeak to moderateNo staining at all
breast cancer no special typeesophagus  squamous cell carcinoma
cholangiocarcinomahigh-grade serous carcinoma
colorectal adenocarcinomaMerkel cell carcinoma
endometrioid endometrial carcinomaoral squamous cell carcinoma
esophagus adenocarcinomapapillary renal cell carcinoma
gastric adenocarcinoma diffuse type
gastric adenocarcinoma intestinal type
lung adenocarcinoma
pancreas ductal adenocarcinoma
prostate adenocarcinoma
urothelial carcinoma
ExpirationIntegrity warranted for 24 months after purchase when handled and stored according to instructions, see below.
Storage instructionsAvoid repeated freeze/thaw cycles. For long term storage, keep small aliquots at -20°C or -80°C and keep one aliquot at 4°C for daily experimentations. Azide will preserve antibody at 4°C for 6-12 months, when kept away from direct sun light.
WarrantyThis product is only warranted for the specifications as described in this product sheet and only when the product is handled and stored according to instructions. User should validate this antibody in the application and tissue/cell type as required, after confirmation of integrity upon receipt is obtained by reproducing the performance as described below. Should such confirmation not be attempted, any warranty is void. In case of non-conformance, user needs to contact us immediately for replacement or refund.
LiabilityThis product is for in vitro research use only. Any other applications, such as diagnostics or therapeutics, or in vivo experiments, and the validation of this product therein, are solely at the responsibility of the buyer/user.
Product Data Sheet
Material Safety Data Sheet

Additional information

Purification

By Protein A from bioreactor concentrate

Immunogen

Recombinant full-length human MUC6 protein

Epitope

Unknown

Cellular localization

secreted

Positive Controls

colorectal adenocarcinoma, duodenum Brunner gland, seminal vesicle, stomach

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